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. 2016 Aug 24;4:e2326. doi: 10.7717/peerj.2326

Table 1. Dengue virus serotype 2 (DENV-2) recombinant strains obtained using RDP4 package.

A total of 26 recombinant strains were identified using RDP4 with p-value < 0.00001. The breakpoint positions are reported according to the position in the respective recombinant sequence. The recombination is detected using at least two of the six recombination detection methods in RDP4 program namely RDP, GENCONV, BOOTSCAN, MAXCHI, CHIMAERA, SISCAN and 3SEQ and are represented as R, G, B, M, C, S and Q, respectively. The method showing comparatively lowest p-value is shown and is represented as bold and the corresponding p-value is also reported.

Serial number Recombinant DENV-2 strain [Genotype_ GenBank-Accession] Major Parent [Genotype_ GenBank-Accession] Minor Parent [Genotype_ GenBank-Accession] Breakpoint start Breakpoint end Methods: RGBMCSQ Lowest p-value
1 AM_GQ398257 AM_GQ868600 AA_GQ398269 4,256 6,361 RGBMCSQ 3.70E−140
2 AM_JQ922552 AM_JQ922550 AM_JQ922549 6,081 6,535 RGBMCS 1.05E−20
3 AM_JQ922553 AM_JQ922552 C_JQ922551 7,448 8,410 RGBMCSQ 1.97E−36
4 AM_JQ922550 AM_JQ922552 C_JQ922551 7,448 8,410 RGBMCSQ 1.97E−36
5 AM_AF100467 AM_EU056811 AM_GQ868588 6,000 7,947 RGBQ 1.23E−18
6 C_EU179859 C_EU482640 Unknown 2,985 3,975 RGBMCSQ 3.56E−84
7 C_FJ196854 C_JN851128 A1_FJ196851 0* 773 RGBS 1.89E−28
C_GQ398264 A1_FJ196851 10,200 10,498* RGB 1.55E−14
8 C_ JQ922551 C_GQ398261 AM_JQ922552 1,544 1,824 RGB 5.428E−08
9 AA_GQ398269 AA_GQ398300 AAF204178 4,289 6,204 RGBMCS 4.51E−53
10 AA_JN819408 AA_GQ868553 Unknown 10,411 10,620* RGBMC 1.41E−69
11 AA_EU482726 AA_EU596491 AA_EU482719 5,260 8,059 GBMCS 1.22E−38
12 AA_JF357906 AA_EU621672 Unknown 10,466 10,783* RGBMCQ 1.60E−113
13 AA_FJ744708 AA_JF357906 Unknown 7,502 7,567 RB 2.97E−08
14 AA_JN819418 AA_M20558 Unknown 10,266 10,576* RGBMC 8.77E−78
15 AA_AF100466 AA_GQ868540 A1_AF100463 0* 606 RGBSQ 6.77E−40
16 AI_FJ196851 AI_GQ868545 C_FJ196852 4,984 5,266 RGB 1.82E−22
AI_GQ868545 C_FJ196853 8,294 9,438 RGBMCSQ 3.33E−44
17 AI_FJ687444 AI_FJ744721 Unknown 10,277 10,363* RGB 6.92E−27
18 AI_EU482784 AI_EU482775 C_EU482640 2,726 3,751 RGBMCSQ 8.50E−73
AI_FM210211 Unknown 9,970 10,679* RGBMC 1.59E−19
19 AI_FJ410193 AI_FM210211 Unknown 0* 59 RGB 2.79E−08
20 AI_FM210211 AI_FJ687444 AA_EU482783 9,988 10,691* RGBMCS 3.04E−29
21 AI_GU131924 AI_FM210211 Unknown 9,955 10,557* RGBMC 1.59E−19
22 AI_JN368476 AI_GU131930 AI_GU131897 8,188 9,896 RGBS 1.14E−12
23 AI_FJ639717 Unknown AI_GU131897 8,317 9,306* RGBSQ 1.14E−12
24 AI_JF730047 Unknown AI_GU131897 8,329 9,318* RGBSQ 1.14E−12
25 AI_GU131930 Unknown AI_GU131897 8,317 9,306* RGBSQ 1.14E−12
26 AI_JF730048 Unknown AI_GU131897 8,328 9,317 RGBSQ 1.14E−12

Notes.

*

Indicates that the actual breakpoint position is undetermined in subsequent recombination event.