Figure 2.

Telomere-length estimates correlate with alternative molecular measurement methods. Scatterplot of TelSeq telomere-length estimates (y-axis) plotted against alternative methods of telomere-length measurement on the x-axis. Alternative methods plotted on the x-axis and their associated Spearman’s rank correlation are (A) qPCR measurements normalized by N2 qPCR telomere-length estimate and scaled relative to the TelSeq N2 telomere-length estimate (ρ = 0.445, P = 0.049), (B) TRF (ρ = 0.699, P = 8.5e⁻⁴), and (C) FISH measurements normalized by N2 FISH telomere-length estimate and scaled relative to the TelSeq N2 telomere-length estimate (ρ = 0.815, P = 1.03e⁻⁵). Gray lines represent the regression lines between TelSeq and each method. Dashed diagonal lines represent identity lines.