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. 2016 Jul 21;204(1):371–383. doi: 10.1534/genetics.116.191148

Figure 3.

Figure 3

GWA of telomere length. (A) GWA of telomere-length residuals (conditioned on DNA library) is visualized using a Manhattan plot. Genomic coordinates are plotted on the x-axis against the negative of the log-transformed P-value of a test of association on the y-axis. The blue bar indicates the Bonferroni-corrected significance threshold (α = 0.05). Blue points represent SNVs above the significance threshold whereas black points represent SNVs below the significance threshold. Light-red regions represent the C.I.s surrounding significantly associated peaks. (B) Shown is the split between TelSeq-estimated telomere lengths (y-axis) by genotype of pot-2 at the presumptive causative allele as boxplots (x-axis). The variant at position 14,524,396 on chromosome II results in a putative F68I coding change. Horizontal lines within each box represent the median, and the box represents the interquartile range (IQR) from the 25th–75th percentile. Whiskers extend to 1.5× the IQR above and below the box. Points represent individual strains.