Table 2.
Results of analysis of factors predicting PFI and MST in feline intermediate- to high-grade lymphoma for all 119 cats
Variable | Median PFI | P-value | MST | P-value |
---|---|---|---|---|
Response to therapy | <0.0001 | <0.0001 | ||
CR (n=42) | 205 | 318 | ||
PR (n=26) | 54 | 85 | ||
NR (n=42) | 21 | 27 | ||
Phenotype | 0.90 | 0.30 | ||
B-cell (n=28) | 55 | 144 | ||
T-cell (n=16) | 53 | 89 | ||
Phenotype (abdominal only) | 0.44 | 0.10 | ||
B-cell (n=16) | 50 | 144 | ||
T-cell (n=13) | 27 | 58 | ||
Anatomic form | 0.41 | 0.17 | ||
Abdominal (n=75) | 50 | 85 | ||
Multicentric (n=19) | 74 | 189 | ||
Mediastinal/intrathoracic (n=14) | 64 | 82 | ||
Renal (n=9) | 23 | 27 | ||
Anatomic form | 0.11 | 0.0499 | ||
Renal (n=9) | 23 | 27 | ||
All others | 56 | 105 | ||
Anatomic form | 0.72 | 0.59 | ||
Abdominal (n=75) | 50 | 85 | ||
All others | 65 | 132 | ||
Subtype | 0.01 | 0.16 | ||
LGL (n=7) | 27 | 105 | ||
All others | 57 | 31 | ||
Anatomic form | 0.07 | 0.18 | ||
Mediastinal (n=14) | 33.5 | 74 | ||
All others | 59 | 105 | ||
Institution | 0.68 | 0.91 | ||
UC Davis (n=50) | 57 | 112 | ||
UW Madison (n=50) | 52 | 92 | ||
Vinca alkaloid | 0.19 | 0.32 | ||
Vincristine (n=89) | 51 | 103 | ||
Vinblastine (n=27) | 74 | 151 | ||
Surgery | 0.67 | 0.68 | ||
No surgery (n=114) | 54 | 91 | ||
Surgery performed (n=5) | 63 | 158 | ||
Anaemia | 0.97 | 0.78 | ||
>25% | 56 | 109 | ||
<25% | 44 | 63 | ||
FeLV status | 0.89 | 0.58 | ||
Negative (n=93) | 54 | 105 | ||
Positive (n=9) | 71 | 91 | ||
FIV status | 0.87 | 0.79 | ||
Negative (n=98) | 55 | 97 | ||
Positive (n=4) | 85.5 | 122 | ||
Breed | 0.58 | 0.55 | ||
Siamese (n=5) | 56 | 93 | ||
Other | 70 | 158 |
[Correction added on 22 October 2015, after first online publication: The values under ‘Media PFI’ and ‘MST’ corresponding to Anatomic Form for Renal (n=9) and All Others were amended; the n value for Abdominal under Anatomic Form has been corrected to 75.]