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. 2016 Sep;186(9):2310–2316. doi: 10.1016/j.ajpath.2016.04.015

Figure 2.

Figure 2

Decreased expression levels of miR-185 (A) and miR-186 (B) in the lungs from patients with idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP). Total RNA was isolated from formalin-fixed, paraffin-embedded lung tissue from 15 patients with IPF and 15 controls. The expression levels of miR-185 and miR-186 were determined by real-time RT-PCR and were normalized to those of the internal control. Fold change relative to the mean of control group was calculated for each specimen and is shown in a dot-plot form. ∗P < 0.05 versus control.