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. 2016 Jun 23;11(9):1597–1605. doi: 10.2215/CJN.09050815

Table 2.

BP, body water, and serum electrolyte levels

Characteristic Inpatient Cohort: Baselinea Outpatient Cohort: Tenapanor Outpatient Cohort: Placebo
Tenapanor, n=8 Placebo, n=8 Baseline,a n=37 Change from Baseline to End of Treatment,b n=35 Baseline,a n=35 Change from Baseline to End of Treatment,b n=34
Predialysis SBP, mmHg 156.0±17.1 145.1±23.9 142.9±25.6 −1.1±24.6c 148.4±22.7 −1.3±22.9
Predialysis DBP, mmHg 86.5±7.9 77.3±16.1 76.8±13.8 −1.6±10.7c 81.6±16.2 −0.1±11.2
Total body water, L 48.0±14.7 50.1±16.8 47.4±10.5d 0.3±5.6e 46.9±13.8c 1.9±5.8f
Extracellular water, L 22.3±8.1 22.7±6.8 22.4±4.8d 0.0±2.9e 21.7±6.2c 0.7±3.2f
Calcium, mg/dlg 8.9±0.6 9.3±0.7 8.9±0.6 0.2±0.7 8.7±0.6 0.0±0.7
Potassium, mEq/Lg 4.8±0.5 4.9±0.5 5.0±0.6 −0.1±0.8 5.4±1.0 −0.2±0.6
Sodium, mEq/Lg 136.0±3.1 136.4±3.0 135.0±3.7 −0.8±3.6 135.5±2.5 0.3±2.7
Phosphate, mg/dlg 6.1±1.8 5.4±1.3 5.2±1.8 −0.8±1.5 6.3±1.9 −0.4±1.6
Carbon dioxide, mEq/Lg 24.1±5.3 24.5±5.2 20.4±3.0 −0.8±2.7 19.3±2.8 1.1±3.3

Values are means±SD. SBP, systolic BP; DBP, diastolic BP.

a

Taken on day 1.

b

Taken on day 29.

c

n=34.

d

n=36.

e

n=33.

f

n=31.

g

Taken before dialysis.

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