Table 3.
Bias, precision, and accuracy of estimating equations stratified for eGFR–based CKD stages (≥60, 30–59, 15–29, and <15 ml/min per 1.73 m2)
| GFR Estimating Equations, ml/min per 1.73 m2 | Percentage Bias (95% CI) | Precision, SD, ml/min per 1.73 m2 | Accuracy 10%, % | Accuracy 30%, % |
|---|---|---|---|---|
| eGFR MDRD | ||||
| ≥60, n=328 | 4.7% (1.0 to 8.3) | 19.5 | 35.0 | 83.5 |
| 30–59, n=697 | −5.7% (−7.9 to −3.6) | 12.1 | 30.1 | 80.5 |
| 15–29, n=109 | 0.4% (−6.8 to 7.6) | 8.1 | 22.9 | 69.7 |
| <15, n=5 | −7.9% (−30.9 to 15.0) | 2.8 | 20.0 | 100 |
| eGFR Cr | ||||
| ≥60, n=404 | 9.4% (6.5 to 12.2) | 16.4 | 39.1 | 83.7 |
| 30–59, n=633 | −0.8% (−3.2 to 1.6) | 11.8 | 33.6 | 80.4 |
| 15–29, n=96 | 3.3% (−4.6 to 11.2) | 8.0 | 28.1 | 66.7 |
| <15, n=6 | −2.4% (−27.5 to 22.8) | 3.3 | 50.0 | 83.3 |
| eGFR CysC | ||||
| ≥60, n=263 | −3.7% (−6.1 to −1.3) | 13.7 | 43.0 | 90.9 |
| 30–59, n=663 | −16.2% (−17.8 to −14.6) | 11.4 | 25.0 | 76.9 |
| 15–29, n=196 | −18.6% (−22.5 to −14.7) | 8.3 | 17.3 | 60.7 |
| <15, n=17 | −17.1% (−31.9 to −2.4) | 6.6 | 23.5 | 58.8 |
| eGFR Cr-CysC | ||||
| ≥60, n=316 | −3.5% (−5.6 to −1.5) | 12.6 | 43.7 | 94.0 |
| 30–59, n=670 | −10.6% (−12.2 to −9.1) | 10.2 | 30.0 | 85.4 |
| 15–29, n=145 | −6.5% (−11.8 to −1.1) | 6.8 | 24.1 | 75.2 |
| <15, n=8 | −5.1% (−19.4 to 9.2) | 2.7 | 50.0 | 87.5 |
95% CI, 95% confidence interval; MDRD, Modification of Diet in Renal Disease; Cr, creatinine; CysC, cystatin C; Cr-CysC, creatinine-cystatin C.