Table 2.
CrCl/iGFR classified by categories based on iGFR and CrCl (CRIC data, n=1342)
| Category | iGFR, ml/min per 1.73 m2, median (5th, 25th, 75th, 95th) | CrCl, ml/min per 1.73 m2, median (5th, 25th, 75th, 95th) | CrCl/iGFR Ratio, median (5th, 25th, 75th, 95th) | CrCl/iGFR, mean±SD |
|---|---|---|---|---|
| iGFR level, ml/min per 1.73 m2 | ||||
| ≥60 (n=330) | 71.5 (60.6, 64.5, 82.2, 101.7) | 72.5 (37.3, 56.5, 89.2, 120.9) | 0.99 (0.45, 0.81, 1.16, 1.50) | 1.00±0.35 |
| 45–59 (n=362) | 51.5 (45.6, 48.1, 55.3, 59.1) | 55.7 (27.3, 45.2, 65.5, 83.3) | 1.07 (0.52, 0.88, 1.26, 1.66) | 1.08±0.35 |
| 30–44 (n=400) | 37.6 (30.8, 33.5, 41.6, 44.2) | 41.2 (19.8, 32.4, 50.6, 67.6) | 1.13 (0.49, 0.89, 1.35, 1.80) | 1.14±0.47 |
| <30 (n=250) | 24.0 (14.6, 20.6, 26.8, 29.4) | 29.8 (13.9, 23.3, 37.0, 54.9) | 1.27 (0.69, 1.01, 1.56, 2.58) | 1.37±0.60 |
| CrCl level, ml/min per 1.73 m2 | ||||
| ≥60 (n=424) | 63.1 (37.7, 51.7, 76.0, 96.1) | 75.2 (61.2, 66.7, 86.8, 120.5) | 1.21 (0.87, 1.05, 1.44, 2.16) | 1.33±0.52 |
| 45–59 (n=333) | 46.6 (27.1, 39.0, 55.0, 67.8) | 51.8 (45.6, 48.2, 55.5, 59.2) | 1.12 (0.75, 0.96, 1.33, 1.90) | 1.18±0.37 |
| 30–44 (n=341) | 36.6 (22.3, 29.6, 46.1, 68.6) | 37.9 (30.7, 34.1, 40.9, 44.3) | 1.04 (0.59, 0.81, 1.26, 1.71) | 1.07±0.38 |
| <30 (n=244) | 28.9 (15.5, 22.2, 38.6, 55.4) | 24.0 (11.4, 19.3, 26.9, 29.6) | 0.78 (0.32, 0.57, 1.02, 1.42) | 0.81±0.35 |
iGFR, measurement of GFR by iothalamate clearance; CrCl, urinary creatinine clearance.