Table 3.
CrCl/iGFR classified by categories based on iGFR and CrCl (simulation data, n=1400)
| Category | iGFR, ml/min per 1.73 m2, median (5th, 25th, 75th, 95th) | CrCl, ml/min per 1.73 m2, median (5th, 25th, 75th, 95th) | CrCl/iGFR Ratio, median (5th, 25th, 75th, 95th) | CrCl/iGFR, mean±SD |
|---|---|---|---|---|
| iGFR level, ml/min per 1.73 m2 | ||||
| ≥60 (n=382) | 67.5 (60.6, 63.1, 74.6, 84.9) | 75.0 (59.5, 68.4, 82.6, 97.9) | 1.09 (0.91, 1.01, 1.18, 1.29) | 1.09±0.12 |
| 45–59 (n=508) | 51.8 (45.9, 48.5, 55.7, 58.8) | 59.1 (41.6, 51.6, 66.0, 76.6) | 1.13 (0.85, 1.00, 1.26, 1.44) | 1.13±0.19 |
| 30–44 (n=373) | 38.1 (30.9, 34.4, 41.7, 44.5) | 43.8 (28.2, 36.6, 51.0, 60.2) | 1.15 (0.76, 0.99, 1.32, 1.57) | 1.15±0.23 |
| <30 (n=137) | 23.5 (12.1, 19.4, 27.2, 29.3) | 27.4 (10.6, 21.2, 34.6, 46.1) | 1.23 (0.56, 0.96, 1.56, 2.03) | 1.30±0.75 |
| CrCl level, ml/min per 1.73 m2 | ||||
| ≥60 (n=614) | 62.2 (46.3, 54.5, 70.0, 81.9) | 71.0 (61.0, 65.4, 78.8, 93.1) | 1.17 (0.97, 1.07, 1.27, 1.48) | 1.18±0.16 |
| 45–59 (n=401) | 47.0 (33.5, 41.5, 52.7, 60.6) | 52.8 (45.9, 49.2, 56.5, 59.4) | 1.11 (0.89, 1.00, 1.26, 1.50) | 1.15±0.20 |
| 30–44 (n=273) | 36.8 (22.4, 31.8, 43.2, 49.8) | 38.9 (31.3, 34.9, 42.2, 44.6) | 1.03 (0.79, 0.91, 1.20, 1.59) | 1.09±0.27 |
| <30 (n=112) | 24.3 (11.9, 19.4, 30.2, 40.0) | 24.0 (9.7, 19.7, 27.1, 29.3) | 0.91 (0.47, 0.72, 1.17, 1.74) | 1.03±0.80 |
iGFR, measurement of GFR by iothalamate clearance; CrCl, urinary creatinine clearance.