Table 5.
Performance for biomarker values as potential predictors of AKI
| Biomarker | Ideal Crude Cutoff | Crude AUCa | GA-Adjusted AUCa |
|---|---|---|---|
| Albumin | 3.69×107 | 0.62 | 0.68 |
| Cystatin C | 1.26×106 | 0.65 | 0.68 |
| EGFb | 5.9×102 | 0.68 | 0.70 |
| NGAL | 4.5×105 | 0.63 | 0.67 |
| OPN | 7.12×105 | 0.65 | 0.67 |
| UMODb | 6.7×105 | 0.71 | 0.73 |
| Clusterin | 3.1×105 | 0.62 | 0.67 |
| α-GST | 4.33×102 | 0.68 | 0.68 |
Unless otherwise noted, values are maximum biomarker levels. Biomarker values are expressed as pg/ml. AUC, area under the curve; GA, gestational age; EGF, epithelial growth factor; NGAL, neutrophil gelatinase-associated lipocalin; OPN, osteopontin; UMOD, uromodulin; α-GST, α-glutathione-S-transferase.
a
Log-transformed before analysis to normalize the distribution.
b
Minimum values.