Table 6.

Performance for biomarker value/urine creatinine as potential predictors of AKI

Biomarker	Ideal Crude Cutoff	Crude AUCa	GA-Adjusted AUCa
Albumin	3.14×108	0.67	0.67
B2M	1.2×108	0.67	0.67
Cystatin C	1.1×107	0.69	0.70
NGAL	4.8×106	0.69	0.67
OPN	5.7×106	0.71	0.69
UMODb	6.9×106	0.64	0.68
Clusterin	2.4×106	0.68	0.66
VEGF	1.2×104	0.64	0.68
α-GST	4.5×103	0.71	0.67

Unless otherwise noted, values are maximum biomarker levels. Biomarker values are expressed as pg/mg creatinine. AUC, area under the curve; GA, gestational age; β2-microglobulin; NGAL, neutrophil gelatinase-associated lipocalin; OPN, osteopontin; UMOD, uromodulin; VEGF, vascular endothelial growth factor; α-GST, α glutathione-S-transferase.

^aLog-transformed before analysis to normalize the distribution.

^bMinimum values.