Table 1.

Baseline characteristics of patients with and without microbleeds

Characteristics	Total, n=404	Without MBs, n=321	With MBs, n=83	P Value
Age, yr	60.2±16.4	57.9±17.1	69.3±8.7	<0.001
Sex, men	241 (59.7%)	180 (56.1%)	61 (73.5%)	0.22
BMI, kg/m2	23.2±4.3	23.3±4.5	23.2±3.4	0.95
Systolic BP, mmHg	130.4±22.2	125±18	152±21	<0.001
Diastolic BP, mmHg	70.2±10.8	69±11	75±10	<0.001
Pulse pressure, mmHg	60.2±18.6	56±15	78±20	<0.001
Serum creatinine, mg/dl	2.66±2.48	2.30±2.28	4.05±2.74	<0.001
BUN, mg/dl	34.7±25.7	30.4±21.7	51.4±32.6	<0.001
eGFR, ml/min per 1.73 m2	38.6±31.0	43.1±31.9	21.1±18.6	<0.001
Proteinuria, g/Cre	2.86±3.42	2.78±3.44	3.12±3.30	0.44
Total protein, g/dl	6.2±1.0	6.2±1.0	6.2±0.9	0.87
Albumin, g/dl	3.3±0.7	3.3±0.7	3.3±0.6	0.62
Total cholesterol, mg/dl	211.2±78.9	214.9±81.4	196.9±66.9	0.06
Triglyceride, mg/dl	155.5±84.7	159.2±85.6	141.4±80.0	0.09
HDL cholesterol, mg/dl	50.1±16.9	50.6±17.0	48.2±16.7	0.25
Non-HDL cholesterol, mg/dl	161.1±73.8	164.3±76.6	148.7±60.9	0.09
CRP, mg/dl	0.09 (0.03–0.28)	0.08 (0.03–0.25)	0.12 (0.06–0.46)	0.67
Hemoglobin, g/dl	11.8±2.5	12.0±2.5	10.9±2.1	<0.001
Calcium, mg/dl	9.47±0.63	9.50±0.63	9.35±0.62	0.05
Phosphate, mg/dl	4.17±1.10	4.02±0.92	4.72±1.50	<0.001
iPTH, pg/ml	133.3±193.2	111.3±137.0	200.5±298.8	<0.001
Smoking behavior	142 (35.1%)	108 (33.6%)	34 (41.0%)	0.25
Presence of diabetes	166 (41.1%)	127 (39.6%)	39 (47.0%)	0.26
Presence of dyslipidemia	149 (36.9%)	114 (35.5%)	35 (42.2%)	0.31
Presence of hypertension	247 (61.1%)	174 (43.1%)	73 (88.0%)	<0.001
Anticoagulation and/or antiplatelet therapy	107 (26.5%)	77 (19.1%)	30 (36.1%)	0.04

MB, silent cerebral microbleed; BMI, body mass index; Cre, creatinine; CRP, C-reactive protein; iPTH, intact parathyroid hormone.