Fig 3. ASM overexpression increased depressive- and anxiety-like behavior in female, but not in male, mice.

Feeding latency in a novel arena after a fasting period of 24 h. Mice were treated with amitriptyline (black bars) or water (grey bars) for 4 weeks before and during behavioral testing (n = 10–13 per group). Shown are means + SEM. p<0.05 * versus water-treated mice; # versus WT mice.