Table 1.
Baseline clinical characteristics of COPD patients and control group
| Characteristics | COPD (n=201) | Control (n=402) | P-value |
|---|---|---|---|
| Age, years | 60.68±8.24 | 60.68±8.23 | |
| Male (%) | 175 (87.1) | 350 (87.1) | |
| Body mass index, kg/m2 | 24.07±3.02 | 24.16±2.73 | 0.685* |
| Height | 1.68±0.069 | 1.67±0.069 | 0.095* |
| Smoking status (%) | <0.001 | ||
| Current smoker | 73 (36.3) | 86 (21.4) | |
| Exsmoker | 95 (47.3) | 166 (41.3) | |
| Nonsmoker | 31 (15.4) | 144 (35.8) | |
| Median pack-years (IQR) | 25 (15.0–40.0) | 20.0 (12.5–35.0) | 0.312 |
| Spirometry | |||
| FEV1 | 2.58±0.59 | 3.04±0.53 | <0.001* |
| FEV1(%) | 88.6±14.94 | 106.0±13.02 | <0.001* |
| FVC | 3.91±0.812 | 3.83±0.66 | 0.241* |
| FVC (%) | 96.8±13.52 | 96.6±11.27 | 0.833* |
| FEV1/FVC | 65.91±6.18 | 79.45±5.13 | <0.001* |
| Hypertension (%) | 59 (29.4) | 121 (30.1) | 0.850** |
| Diabetes mellitus (%) | 27 (13.5) | 67 (16.7) | 0.313** |
| Chronic kidney disease (%) | 1 (0.5) | 10 (2.5) | 0.111** |
| Iron deficiency anemia (%) | 0 (0) | 2 (0.5) | 0.555** |
| Cardiovascular disease (%) | 0.711** | ||
| Coronary artery disease | 3 (1.5) | 8 (2.0) | |
| Cerebrovascular disease | 2 (1.0) | 2 (0.5) |
Notes: Continuous data are shown as mean ± SD,
*
P-value from t-test,
**
P-value from Fisher’s exact test.
Abbreviations: FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; IQR, interquartile range; SD, standard deviation.