Table 4.
Univariate and multivariate analysis of Helicobacter pylori seropositivity
| Variables | Seropositivity
|
CLO positivity
|
||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | Unadjusted OR (95% CI) | P-value | Adjusted OR (95% CI) | P-value | |
| Smoking | 0.857 (0.602–1.220) | 0.391 | 0.909 (0.630–1.313) | 0.612 | 1.304 (0.668–2.544) | 0.464 | 1.296 (0.647–2.596) | 0.464 |
| CVD | 1.510 (0.531–4.297) | 0.440 | 1.340 (0.467–3.845) | 0.586 | 0.991 (0.231–4.250) | 0.990 | 0.900 (0.208–3.899) | 0.888 |
| Gastritis/peptic ulcer | 1.343 (0.761–2.371) | 0.309 | 1.132 (0.629–2.037) | 0.679 | 4.4 (0.532–36.372) | 0.169 | 3.961 (0.468–33.519) | 0.207 |
| GERD | 0.482 (0.322–0.721) | <0.001 | 0.485 (0.321–0.733) | 0.001 | 0.494 (0.241–1.013) | 0.054 | 0.527 (0.254–1.091) | 0.084 |
| COPD | 0.772 (0.550–1.084) | 0.135 | 0.778 (0.546–1.108) | 0.164 | 1.023 (0.597–1.755) | 0.933 | 1.014 (0.577–1.781) | 0.963 |
Note: P-value from multiple logistic regression analysis, adjusting for sex, age, smoking status, gastric diseases known to be related to H. pylori infection, and the severity of airflow limitation as defined by FEV1.
Abbreviations: CI, confidence interval; GERD, gastroesophageal reflux disease; OR, odds ratio; CVD, cardiovascular disease.