Table 3. Patient Characteristics (n=26).
| N | % | |
|---|---|---|
| Sex | ||
| Male | 25 | 96% |
| Female | 1 | 4% |
| Age | ||
| Median (range) | 31 | (18.8–47.8) |
| Histology | ||
| Non-seminoma | 21 | 81% |
| Seminoma | 5 | 19% |
| Primary Site | ||
| Testis | 15 | 58% |
| Mediastinum | 6 | 23% |
| Retroperitoneum | 3 | 12% |
| Ovary | 1 | 4% |
| Pineal Gland | 1 | 4% |
| Sites of Metastatic Disease | ||
| Lung | 15 | 58% |
| Retroperitoneum | 12 | 46% |
| Mediastinum | 8 | 31% |
| Liver | 6 | 23% |
| Other*a | 5 | 19% |
| Number of Metastatic Sites | ||
| 1 | 3 | 12% |
| 2 | 7 | 27% |
| 3+ | 16 | 61% |
| Elevated markers | ||
| HCG >2.2mIU/mL | 16 | 62% |
| Median elevated (range) | 869.6 | (4.9–26,652.3) |
| AFP >15ng/mL | 10 | 38% |
| Median elevated (range) | 160.8 | (26.4–2,049.5) |
| LDH >ULN (200/246)b | 8 | 31% |
| Median × ULN (range) | 1.72 | 1.07–3.44 |
| Late Relapse | 1 | 4% |
Abbreviations: HCG = human chorionic gonadotropin; AFP = alpha-fetoprotein; LDH = lactate dehydrogenase; ULN = upper limit of normal
a
Other sites of metastases include brain (2) and adrenal gland, kidney, intestine, and bone in 1 each.
b
ULN changed from 200 to 246 U/L on 04/28/2009