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. 2016 May 31;34(24):2827–2834. doi: 10.1200/JCO.2015.65.7874

Table 3.

Psychological and QOL Outcomes at Baseline and 6 and 12 Weeks for MBSR(BC) and UC Groups and Estimates of Treatment Effects

Psychological Outcome Measure Experimental Group (MBSR[BC]) Control Group (UC) Between-Groups Effect Size Adjusting for Baseline
Mean SD No. Mean SD No. d 95% CI
Depression (CES-D)
 T1 baseline 10.87 6.89 167 10.04 6.46 155
 T2 week 6 8.12 5.45 154 8.82 6.05 146 0.20 0.00 to 0.40
 T3 week 12 8.66 6.26 155 8.95 6.8 148 0.16 −0.05 to 0.36
 P* .06
Anxiety (STAI-S)
 T1 baseline 38.62 12.3 167 35.86 11.29 155
 T2 week 6 30.62 12.8 159 31.76 13.2 152 0.26 0.06 to 0.46
 T3 week 12 31.82 12.1 155 32.99 13.4 148 0.27 0.06 to 0.47
 P* .007
FOR—overall (CARS)
 T1 baseline 12.29 5.64 167 10.75 5.57 155
 T2 week 6 9.77 5.34 154 9.85 5.4 146 0.30 0.10 to 0.50
 T3 week 12 9.25 5.28 161 9.61 5.77 155 0.28 0.08 to 0.48
 P* .001
FOR—problems (CARS)
 T1 baseline 39.43 24.4 167 31.84 24.5 155
 T2 week 6 28.51 24.04 152 29.87 25.7 145 0.46 0.25 to 0.66
 T3 week 12 28.36 24.54 153 28.01 26.01 146 0.35 0.15 to 0.56
 P* .001
QOL—general health (MOS SF-36)
 T1 baseline 62.63 21.24 167 66.29 20.76 155
 T2 week 6 67.93 19.87 152 68.28 21.28 145 0.16 −0.04 to 0.37
 T3 week 12 68.76 21.50 153 67.85 21.99 146 0.21 0.01 to 0.42
 P* .05

Abbreviations: CARS, Concerns About Recurrence Scale; CES-D, Center for Epidemiologic Studies Depression Scale; FOR, fear of recurrence; MBSR(BC), Mindfulness-Based Stress Reduction for Breast Cancer; MOS SF-36, Medical Outcomes Study Short Form; QOL, quality of life; SD, standard deviation; STAI-S, State-Trait Anxiety Inventory–State; T, time point; UC, usual care.

*

Linear mixed-model interaction: time point by treatment group assignment.