Table 1.
Characteristics of Cohorts Participating in the Ovarian Cancer Cohort Consortium
| Study Name | Study Acronym | Location | Baseline Enrollment Period | Baseline Cohort Size* | Median Study Participant Age (years) | Median Follow-Up (years) | Last Year of Follow-Up | Invasive Ovarian Cancer Cases |
|---|---|---|---|---|---|---|---|---|
| NIH-AARP Diet and Health Study | AARP | US | 1995-1997 | 153,069 | 62 | 11 | 2006 | 703 |
| Breast Cancer Detection Demonstration Project Follow-Up Study | BCDDP | US | 1987-1989 | 36,212 | 61 | 9 | 1999 | 159 |
| Breakthrough Generations Study | BGS | UK | 2001-2014 | 101,869 | 48 | 6 | 2014 | 75 |
| Canadian Study of Diet, Lifestyle, and Health | CSDLH | Canada | 1991-1999 | 2,745† | 58 | 16 | 2010 | 90 |
| Campaign Against Cancer and Stroke | CLUEII | US | 1989 | 12,382 | 46 | 22 | 2012 | 82 |
| Cancer Prevention Study II Nutrition Cohort | CPSII-NC | US | 1992-1993 | 65,884 | 62 | 15 | 2009 | 533 |
| California Teachers Study | CTS | US | 1995-1999 | 43,778 | 50 | 15 | 2010 | 185 |
| European Prospective Investigation Into Cancer and Nutrition Study | EPIC | Europe | 1992-2000 | 263,796 | 51 | 13 | 2010 | 671 |
| Iowa Women’s Health Study | IWHS | US | 1986 | 30,537 | 61 | 23 | 2010 | 263 |
| Multiethnic/Minority Cohort Study‡ | MEC | US | 1993-1998 | 16,474 | 57 | 11 | 2011 | 75 |
| Nurses’ Health Study 1980§ | NHS80 | US | 1980-1982 | 86,608 | 46 | 16 | 1998 | 351 |
| Nurses’ Health Study 1996§ | NHS96 | US | 1996-1998 | 67,530 | 62 | 14 | 2010 | 417 |
| Nurses’ Health Study II | NHSII | US | 1989-1990 | 111,800 | 35 | 20 | 2011 | 215 |
| New York University Women’s Health Study | NYU | US | 1984-1991 | 12,427 | 49 | 24 | 2012 | 129 |
| Netherlands Cohort Study on Diet and Cancer | NLCS | Netherlands | 1986 | 2,757† | 62 | 17 | 2003 | 448 |
| Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial | PLCO | US | 1993-2002 | 60,191 | 62 | 12 | 2009 | 358 |
| Singapore Chinese Health Study | SCHS | Singapore | 1993-1999 | 31,939 | 56 | 14 | 2011 | 95 |
| Sister Study | SS | US | 2003-2009 | 39,195 | 55 | 5 | 2012 | 39 |
| Swedish Mammography Cohort Study | SMC | Sweden | 1997 | 34,427 | 60 | 14 | 2011 | 161 |
| Vitamins and Lifestyle Cohort | VITAL | US | 2000-2002 | 28,331 | 60 | 10 | 2011 | 130 |
| Women’s Lifestyle and Health Study | WLHS | Sweden | 1991-1992 | 49,087 | 40 | 21 | 2012 | 201 |
| Women’s Health Study | WHS | US | 1993-1996 | 33,548 | 53 | 18 | 2012 | 204 |
Abbreviation: NIH, National Institutes of Health.
*
After exclusions for baseline cancers and women with bilateral oophorectomy.
†
These cohorts were included as a case-cohort design, which reflected a total cohort population of 39,618 women for the CSDLH and 62,573 women for the NLCS. Appropriate weights for subcohort selection were applied in all analyses.
‡
Included only white women.
§
The Nurses’ Health Study was broken into two study periods (1980 to June 1996 and July 1996 to 2010) because the follow-up was nearly twice as long as any other study. We updated the exposures in 1996 for that follow-up period.