Table 2.

Tumor Characteristics

Characteristic	Chemotherapy Only (n = 635)	Cystectomy Only (n = 413)	Cystectomy + Preoperative Chemotherapy (n = 363)	Cystectomy + Adjuvant Chemotherapy (n = 328)	P
Clinical T stage					< .001
T0	1 (0)	1 (0)	1 (0)	0 (0)
T1	62 (10)	13 (3)	20 (6)	8 (2)
T2	243 (38)	110 (26)	131 (36)	80 (24)
T3	112 (18)	133 (32)	86 (24)	107 (33)
T4	137 (22)	109 (26)	65 (18)	83 (25)
Tx	39 (6)	12 (3)	13 (4)	14 (4)
Not applicable	41 (6)	35 (8)	47 (13)	36 (11)
Clinical N stage					< .001
N1	262 (41)	218 (53)	200 (55)	153 (47)
N2	309 (49)	181 (44)	139 (38)	161 (49)
N3	64 (10)	14 (4)	24 (7)	14 (4)
Pathologic T stage					< .001
T0	3 (0)	3 (1)	46 (13)	1 (0)
T1	15 (2)	9 (2)	15 (4)	4 (1)
T2	73 (11)	77 (19)	70 (19)	49 (15)
T3	23 (4)	188 (46)	123 (34)	162 (49)
T4	17 (3)	112 (27)	55 (15)	88 (27)
Tx	427 (67)	20 (5)	41 (11)	18 (5)
Not applicable	77 (12)	4 (1)	13 (4)	6 (2)
Pathologic N stage					< .001
N0	12 (2)	28 (7)	133 (37)	10 (3)
N1	31 (5)	140 (34)	66 (18)	109 (33)
N2	45 (7)	194 (47)	90 (25)	163 (50)
N3	6 (1)	15 (4)	23 (6)	15 (5)
Nx	465 (73)	32 (8%)	38 (10%)	25 (8%)
Not applicable	76 (12%)	4 (1%)	13 (4%)	6 (2%)
Surgical margin status					< .001
Negative	74 (12%)	305 (74%)	293 (81%)	250 (76%)
Positive	120 (19%)	87 (21%)	50 (14%)	62 (19%)
Not evaluable	288 (45%)	9 (2%)	12 (3%)	8 (2%)
No surgical procedure	91 (14%)	0 (0)	0 (0)	0 (0)
Missing	62 (10%)	12 (3%)	8 (2%)	8 (2%)
Nodes examined					< .001
0	493 (78%)	13 (3%)	31 (9%)	12 (0.04)
1+	85 (13%)	388 (94%)	318 (87%)	311 (0.95)
Median	0 (0-0)	9 (4-18)	15 (6-24)	10 (5-19)	< .001
By aspiration	36 (6%)	0 (0)	3 (1%)	0 (0)
Unknown	21 (3%)	12 (3%)	11 (3%)	5 (0.02)
Median time to cystectomy, months	—	1.6 (1.0-2.5)	5.4 (4.3-6.3)	1.4 (0.8-2.0)	< .001

NOTE: Data are presented as median (interquartile range) for continuous variables and as frequencies (%) for categorical data.