Table 2.
Personal History of Malignancies in Patients With MMR-Deficient Rectal Cancers
| Cancer Type | Before Rectal Cancer | Metachronous to Rectal Cancer |
|---|---|---|
| Colon | 4 (6.4) | 8 (16.7)* |
| Distal | 1 | 7 |
| Proximal | 4 | 1 |
| Extracolorectal | 14 (22.6) | 14 (22.6) |
| Endometrial | 6 | 4 |
| Urothelial/transitional | 2 | 2 |
| Small bowel | 1 | 2 |
| Gastric | 1 | |
| Pancreatic | 1 | |
| Sebaceous skin | 1 | 1 |
| Ependymal | 1 | |
| Sarcoma | 1 | 1 |
| Lymphoma/leukemia | 2 | 1 |
| Breast | 1 | |
| Squamous cell skin† | 2 | 5 |
| Cervix/vagina | 1 | 1 |
| Lung | 1 | 2 |
| Prostate | 1 |
NOTE. Data presented as No. of patients (%).
Abbreviation: MMR, mismatch repair.
*
Among 48 patients with remaining at-risk colon.
†
Eyelid, cheek, foot, thumb, scalp.