Skip to main content
. Author manuscript; available in PMC: 2017 Mar 18.
Published in final edited form as: Circ Res. 2016 Jan 7;118(6):994–1007. doi: 10.1161/CIRCRESAHA.115.305376

Table 1.

Summary of known genomic function associated with ERα and ERβ

ERα ERβ

  • Increases left ventricular mass and volume159;

  • Reductions of infarct size after myocardial infarction159;

  • Cardioprotection against ischemia-reperfusion injury160–162;

  • Regulates GLUT4 expression163;

  • Regulates cardiac growth164.

  • Reduces pathologic cardiac hypertrophy4;

  • Prevents increases mortality in chronic heart failure165, 166;

  • Cardioprotection against ischemia-reperfusion injury41;

  • Regulation of vascular function and blood pressure133;

  • modulates sex-specific response of the heart to exercise50;

  • Decreases inflammatory response41.