Table 2.
Crude Odds Ratio (COR) and age-adjusted Odds Ratio (AOR) for socio-demographic characteristics associated with Nodding syndrome
| Status of study Participants | ||||||||
|---|---|---|---|---|---|---|---|---|
| Variables | Cases = 66 (47%) | Controls = 73 (53%) | COR | 95% CI | P-value | AOR | 95% CI | P-value |
| 3-Hydroxykynurenine | ||||||||
| Negative (below detection limit) | 34 (52) | 61 (84) | 1 | 1 | ||||
| Positive (above detection limit) | 32 (48) | 12 (16) | 4.78 | 2.18 - 10.49 | ≤0.001 | 4.50 | 1.37 - 14.77 | 0.013 |
| Vitamin B6 level in plasma (pmol/l) | ||||||||
| Above mean (365.603 - 1350.36) | 8 (12) | 42 (58) | 1 | 1 | ||||
| Below mean (8.15 - 365.602) | 58 (88) | 31(42) | 9.82 | 4.10 - 23.51 | ≤0.001 | 7.22 | 2.24 - 23.26 | 0.001 |
| Gender | ||||||||
| Female | 20 (30) | 39 (53) | 1 | 1 | ||||
| Male | 46 (70) | 34 (47) | 2.63 | 1.31 - 5.30 | 0.006 | 2.23 | 0.78 - 6.34 | 0.158 |
| Care taker of the child | ||||||||
| Father & Mother | 26 (41) | 55 (76) | 1 | 1 | ||||
| Father | 2 (3) | 1 (1) | 4.23 | 0.37 - 48.80 | 0.248 | 0.90 | 0.05 - 15.44 | 0.943 |
| Mother | 21 (33) | 10 (14) | 4.44 | 1.83 - 10.77 | 0.001 | 5.43 | 1.48 - 19.87 | 0.011 |
| Guardian | 14 (22) | 6 (8) | 4.94 | 1.70 - 14.30 | 0.003 | 5.90 | 1.34 - 25.93 | 0.019 |
| Child exclusively breast fed | ||||||||
| No | 5 (8) | 2 (3) | 1 | |||||
| Yes | 55 (92) | 69 (97) | 0.32 | 0.06 - 1.71 | 0.182 | 0.18 | 0.02 - 1.65 | 0.131 |
| Source of food consumed at weaning | ||||||||
| Home grown food | 20 (33) | 49 (73) | 1 | 1 | ||||
| Relief food | 40 (67) | 18 (27) | 5.44 | 2.54 - 11.66 | ≤0.001 | 4.05 | 1.23 - 13.28 | 0.021 |
| Mother was feeding well when breastfeeding the child | ||||||||
| No | 22 (36) | 10 (14) | 1 | |||||
| Yes | 39 (64) | 62 (86) | 0.29 | 0.12 - 0.67 | 0.004 | 0.90 | 0.27 - 3.00 | 0.867 |