TABLE 2.

EXCLUSION CRITERIA

History of prior treatment for choroidal melanoma

Presence of diabetic retinopathy

History of retinal vascular occlusion or other retinal vascular disease

Active ocular inflammation or history of uveitis in either eye

History of uncontrolled glaucoma (defined as intraocular pressure >30mmHg despite treatment with anti-glaucoma medication) or filtering surgery in the study eye

History of allergy to fluorescein

Inability to obtain fundus photographs of sufficient quality

Inability to comply with study or follow-up procedures

Previous intravitreal injections of bevacizumab in the study eye or in the non-study eye within 30 days.

Concurrent use of systemic anti-VEGF* therapy

Current treatment for active systemic infection

Pregnancy or lactation

History of other disease, metabolic dysfunction, physical examination finding or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of an investigational drug or that might affect interpretation of the results of the study or render the subject at high risk for treatment complications.

Participation in another simultaneous medical investigation or trial

Any other condition that the investigator believes would pose a significant hazard to the subject if the investigational therapy were initiated