TABLE 3.

BASELINE CHARACTERISTICS

	SMALL/MEDIUM			LARGE
	RBZ+PBI n=25	PBI n=100	P	RBZ+PBI n=15	PBI n=275	P
Age at Tx (mean, years)	59.4 (40.9–84.5)	57.9 (19.5–8.0)	.80*	54.8 (28.3–86.2)	57.3 (15.2–91.9)	.39*
Gender (% male)	14 (56.0)	51 (51)	.66^	8 (53.3)	129 (46.9)	.79^
LTD (Mean, mm)	10.78 (6.5–15)	10.55 (6–15)	.63*	17.27 (11–24)	15.78 (9–22)	.08*
Height (Mean, mm)	2.76 (1.7–4.6)	2.86 (1–5.5)	.54*	7.32 (2.1–15.6)	7.9 (1.8–17.1)	.32*
Distance to optic disc (mean, DD)	1.68 (0–4)	1.16 (0–4)	.05*	2.47 (0–8)	2.39 (0–8)	.81*
Distance to macula (mean, DD)	1.08 (0–5)	0.94 (0–5)	.69*	2.27 (0–7)	2.37 (0–8)	.70*
Radiation dose 70 Gy (%)	6 (24.0)	6 (6.0)	.01^	15 (100)	275 (100)	---
Baseline VA ≥ 20/40 (%)	22 (88.0)	68 (68.0)	.05^	8 (55.3)	130 (47.3)	.79^
Baseline VA ≥ 20/200 (%)	25 (100)	100 (100)	---	12 (80.0)	225 (81.8)	.74^

^*Mann-Whitney test

^{^}Fisher’s exact test

RBZ: ranibizumab; PBI: proton beam irradiation; Tx: treatment; LTD: largest tumor diameter; DD: disc diameter; Gy: Gray; VA: visual acuity