Table 5.

Hsp90 docking results of combined inhibitors

Name	Target	Total Score	Crash	Polar	Similarity
AUY922	Hsp90	11.3281	−2.9912	5.8905	0.566
KOSN1559	Hsp90	10.5386	−4.2057	6.0038	0.497
GDM	Hsp90	9.0405	−4.3587	5.7304	0.506
3t	Topo II	8.9981	−1.9006	2.2646	0.451
KF58333	Hsp90	8.8035	−2.216	3.7782	0.475
PU3	Hsp90	8.6779	−1.3914	2.3162	0.465
Comp. 14	Topo II	8.0945	−2.9386	4.3295	0.547
o-RDC	Hsp90	7.4652	−3.5968	3.1916	0.421
CCT018159	Hsp90	7.4339	−0.7895	3.2601	0.521
SNX0723	Hsp90	7.1997	−2.4905	1.3399	0.526
Salvicine S	Topo II	7.1362	−1.4093	1.6745	0.475
AT13387	Hsp90	7.1259	−2.0725	1.7217	0.519
Comp. 14mod	Topo II	7.0102	−2.3685	3.184	0.519
G3130	Hsp90	6.8551	−0.5655	4.089	0.514
QAP1	Topo II	6.7837	−2.2874	0.9711	0.497
CPUY201112	Hsp90	6.7467	−2.5928	2.7711	0.612
NSC348400	Topo II	6.7386	−1.4421	3.7083	0.511
RDC	Hsp90	6.6884	−2.5576	3.4177	0.666
NSC35866	Topo II	6.649	−1.1619	2.6058	0.486
Salvicine R	Topo II	6.4918	−2.4288	2.1968	0.510
Comp. 1	Topo II	6.4641	−1.627	2.2857	0.561
2c	Topo II	6.4036	−3.4089	0.0014	0.329
KF25706	Hsp90	6.185	−2.8315	3.6404	0.647
Gambogic acid	Topo II	6.0092	−2.2055	1.3905	0.297
Comp. 2	Topo II	5.952	−1.2823	1.4835	0.524
Daurinol	Topo II	5.8292	−0.4604	1.3936	0.556
KF29163	Hsp90	5.7498	−2.3134	1.6213	0.530
17-DMAG	Hsp90	5.718	−3.6373	1.0756	0.318
c-RDC	Hsp90	5.6849	−3.5861	3.0525	0.691
Comp. 5	Topo II	5.6657	−1.6574	1.9241	0.430
D11	Topo II	5.6512	−0.8901	2.5246	0.390
Emodin	Topo II	5.6113	−0.429	1.9987	0.398
8-Cl-ATP	Topo II	5.5933	−1.2132	4.7994	0.399
Pochonin D	Hsp90	5.5041	−1.5103	2.1344	0.550
TSC24	Topo II	5.477	−1.2353	0.5795	0.418
Pochonin A	Hsp90	5.4494	−1.3695	2.6113	0.279
17-AAG	Hsp90	5.2911	−2.6657	0.545	0.301
Aigialomycin D	Hsp90	4.8757	−3.236	3.4461	0.549
Comp. 18	Topo II	4.553	−0.4098	0.9114	0.427