Table 1.

The antiviral activity of norwogonin, oroxylin A, mosloflavone and ribavirin against EV71

	Enterovirus 71
	CC50a	IC50b	TIc
Norwogonin	> 50	31.83 ± 6.21	> 1.57
Oroxylin A	> 50	14.19 ± 4.22	> 3.52
Mosloflavone	> 50	37.72 ± 0.78	> 1.33
Ribavirin	> 50	NDd	-

Results are presented as the mean IC₅₀ values ± standard deviation (SD) obtained from 3 independent experiments each carried out in triplicate.

^aConcentration required to reduce cell growth by 50% (μg/mL).

^bConcentration required to inhibit virus-induced CPE by 50% (μg/mL).

^cTherapeutic index = CC₅₀/IC₅₀.

^dNot determined.