Representative images of liver histology from DIAMOND mice (a,c,e,g,i,k) or human NASH (b, d, f, h, j, l) depicting steatosis (a, b; H&E; original magnification, ×5), Hepatocyte ballooning (c, d; H&E; original magnification, ×40), Mallory-Denk bodies (as indicated by large arrow) (e, f; H&E; original magnification, ×40), Stage 1 fibrosis (g, h; Sirius Red; original magnification, ×20), Stage 2 fibrosis (i, j; Sirius Red; original magnification, ×20), Stage 3 fibrosis (k, l; Sirius Red; original magnification, ×10). CV, central vein; PT, portal tract.