Table 2.

Effect of monotherapies and dual therapies on neuronal injury assessed by fluoro-jade B staining.

	SE control (n= 5)	Valp 270 mg/kg (n=5)	Mz 9mg/kg (n=10)	Ket 90 mg/kg (n=7)	Mz 4.5 + Ket 45 (n= 9)
Frontoparietal cortex	4 (1-4)	4 (4)	2 (1-4)	1 (1) *••	1 (1-2) *••
Entorhinal cortex	4 (4)	4 (4)	1 (1-4)	1 (1) **••	1 (1) **••
Piriform cortex	4 (4)	4 (4)	1 (1-4)	1 (1) **••	1 (1-2) **••
Thalamus	4 (1-4)	4 (3-4)	2 (1-4)	1 (1-2) •	1 (1) *••
Amygdala	4 (4)	4 (4)	2 (1-4)	1 (1-2) *•	1 (1) **••

The first numbers represent the median damage score. The numbers in parentheses indicate the range of neuronal injury.

^*p < 0.05 or

^**p <0.01 vs SE control

^•p <0.05 or

^••p <0.01 vs valproate.