Table 3. Treatment course of patientsφ.
| Characteristic | Only PTB n=99 (% or SD) | Some form of EPTB n=64 (% or SD) | p-value |
|---|---|---|---|
| Treatment outcome* | 0.256 | ||
| Treatment success† | 81 (89.0) | 47 (82.5) | |
| Death | 10 (11.0) | 10 (17.5) | |
| Mean treatment duration in weeks (SD)** | 31.8 (8.1) | 37.9 (11.7) | <0.001 |
| Mean treatment duration in weeks by site EPTB | <0.001 | ||
| Lymph Node | 32.9 (8.5) | ||
| Pleural | 32.8 (6.1) | ||
| Bone | 50.3 (11.1) | ||
| CNS TB | 58.5 (9.2) | ||
| GI | 34.7 (10.8) | ||
| Miliary | 42 (13) | ||
| Hospitalization at time of diagnosis | 48 (48.5) | 37 (57.8) | 0.244 |
| Subsequent hospitalization*** | 20 (20.2) | 25 (39.1) | 0.009 |
PTB= pulmonary tuberculosis; EPTB=extrapulmonary tuberculosis; CNS=central nervous system; GI=gastrointestinal; SD=standard deviation
Treatment outcome, hospitalization at time of diagnosis, and subsequent hospitalization analyzed using Pearson's χ squared tests. Mean treatment duration by site of TB and treatment outcome by age of presentation analyzed using one-way analysis of variance and student's t-tests.
Outcomes available for 148 patients (7 transferred out, 3 lost to follow up, and 5 still on treatment at time of analysis). More persons with only EPTB had an outcome of death compared to only PTB and EPTB/PTB; was not significant (8/40 [20.0%]; 10/91 [11.0%]; 2/17 [11.8%] for only EPTB, only PTB, and EPTB/PTB, respectively; p=0.371).
Treatment success = alive and cured of TB at end of treatment. Persons who had treatment success were younger than those who did not (mean age 44.7 [SD=19.9] vs. 63.3 [SD=19.2]; p<.001).
Data analyzed on 127 patients (20 patients who died and 1 MDR-TB patient excluded). There was a difference in mean treatment duration comparing those with EPTB only (n=32, mean duration 37.9 weeks) to some form of PTB (n=95, mean duration of 32.8 weeks; p=.012).
Subsequent hospitalization = any hospitalization after treatment was initiated