Appendix Table 2.
Sensitivity of economic outcomes to variation in key input parameters in a modeling analysis of 90-90-90 in South Africa.*
| Basecase | 5 yr | 10 yr |
|---|---|---|
| Current Pace total cost | $18,674 | $38,353 |
| UNAIDS Target total cost | $26,639 | $54,332 |
|
| ||
| UNAIDS Target additional cost | $7,965 | $15,979 |
|
| ||
| ICER ($/YLS) | $2,720 | $1,260 |
|
| ||
| Testing/linkage efficiency (25%), Adherence/retention intervention cost (200%) | 5 yr | 10 yr |
|
| ||
| Current Pace total cost | $18,674 | $38,353 |
| UNAIDS Target total cost | $31,445 | $64,370 |
|
| ||
| UNAIDS Target additional cost | $12,771 | $26,016 |
|
| ||
| ICER ($/YLS) | $4,330 | $2,040 |
|
| ||
| Testing/linkage efficiency (90%), Adherence/retention intervention cost (50%) | 5 yr | 10 yr |
|
| ||
| Current Pace total cost | $18,674 | $38,353 |
| UNAIDS Target total cost | $24,343 | $49,533 |
|
| ||
| UNAIDS Target additional cost | $5,668 | $11,180 |
|
| ||
| ICER ($/YLS) | $1,940 | $890 |
|
| ||
| ART costs (50%) | 5 yr | 10 yr |
|
| ||
| Current Pace total cost | $17,002 | $34,579 |
| UNAIDS Target total cost | $23,784 | $47,525 |
|
| ||
| UNAIDS Target additional cost | $6,782 | $12,947 |
|
| ||
| ICER ($/YLS) | $2,270 | $980 |
|
| ||
| ART costs (50%), testing/linkage efficiency (90%), Adherence/retention intervention cost (50%) | 5 yr | 10 yr |
|
| ||
| Current Pace total cost | $17,002 | $34,579 |
| UNAIDS Target total cost | $21,487 | $42,726 |
|
| ||
| UNAIDS Target additional cost | $4,485 | $8,147 |
|
| ||
| ICER ($/YLS) | $1,490 | $600 |
Abbreviations: ICER, incremental cost-effectiveness ratio; YLS, years of life saved
*
All costs are reported in 2014 USD. Total costs are reported undiscounted, in millions; ICERs are calculated as Δ$/ΔYLS of UNAIDS Target strategy compared to Current Pace strategy. Discounted values at 3% per year are used for incremental cost-effectiveness ratios.