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Human APP‐transgenic mouse and rat models analysed
| Animal model | ||||||
|---|---|---|---|---|---|---|
| Wild‐type mouse | I5 mouse | Tg2576 mouse | 3xTg mouse | Wild‐type rat | McGill‐APP rat | |
| Promoter | – | PDGF α chain | Hamster prion protein | Mouse Thy1.2 | – | Rat Thy1.2 |
| Transgene | – | hAPP770wt | hAPP695swe | hAPP695swe | – | hAPP751swe/ind |
| Genetic background | C57BL/6 | C57BL/6 | C57BL/6 × SJL | C57BL/6 × 129sv | Wistar | Wistar |
