Table 1.
Differences in clinical risk factors between OPVHs patients and CN.
| Group | OPVHs | CN | χ2/t | p |
|---|---|---|---|---|
| n | 97.00 | 73.00 | ||
| Gen (n, %male)1 | 61 (62.89) | 35 (47.95) | 3.78 | 0.05 |
| Age (years)2 | 71.79 (8.29) | 68.9 (7.91) | −4.87 | 0.00* |
| Fazekas score | 2.73 (0.54) | 0.0 (0.00) | \ | \ |
| CS (n, %)1 | 24 (24.74) | 21 (28.77) | 0.35 | 0.56 |
| CAU (n, %)1 | 21 (21.65) | 14 (19.18) | 0.16 | 0.69 |
| Htn (n, %)1 | 47 (48.45) | 26 (35.62) | 2.80 | 0.09 |
| DM (n, %)1 | 18 (18.56) | 8 (10.96) | 1.86 | 0.17 |
| TC2 | 4.61 (1.07) | 4.81 (0.96) | 2.05 | 0.04* |
| TG2 | 1.44 (0.76) | 1.66 (1.17) | 1.48 | 0.14 |
| LDL_C2 | 2.51 (0.63) | 2.83 (0.68) | 3.20 | 0.00* |
| HDL_C2 | 1.34 (0.32) | 1.29 (0.30) | −0.95 | 0.34 |
| UA2 | 289 (75.30) | 277.75 (67.33) | −1.01 | 0.31 |
| Apo-A12 | 1.30 (0.31) | 1.25 (0.33) | −1.01 | 0.31 |
| Apo-B2 | 0.84 (0.24) | 0.91 (0.23) | 2.24 | 0.03* |
Data are presented as the means (standard deviation). Chi-square tests and Student’s t-test were used to determine significant differences in the frequencies of categories and differences in continuous variables, respectively, between the groups. TC, LDL-C and Apo-B were significantly lower in the OPVHs patients compared to the CN (p < 0.05). Regarding age, OPVHs patients were significantly older than the CN. It should be noted that the Gen, CS, DM, CAU, and Htn had no significant differences. Abbreviations are as follows: OPVHs, occipital periventricular hyperintensities; CN, healthy controls, Gen, gender; CS, current smoking; CAU, current alcohol use, Htn, hypertension; DM, diabetes mellitus; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; UA, uric acid; Apo-A1, apolipoprotein-A1; and Apo-B, apolipoprotein-B; 1, 2, *denote chi-square test, Student’s t-test and p < 0.05, respectively.