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. 2016 Sep 7;7:386. doi: 10.3389/fphys.2016.00386

Figure 3.

Figure 3

Effects of high-sugar diet and exercise training on aorta contractility. Concentration-dependent contraction response to phenylephrine (Phen) in the presence (A) or absence (C) of a functional endothelium, n = 10. (B) Area under the curve (AUC) calculated from (A). (D) Contractile response to Phen in the aortas from sedentary animals in the presence or absence of L-NAME (300 μM), n = 8. (E) The area under the curve (AUC) calculated from (D). (F) Contractile response to KCl, n = 5. Data represent mean ± SEM. Differences in maximal contractions are shown in concentration-response curves. *p < 0.05, **p < 0.01, and ***p < 0.001; two-way ANOVA with Tukey post-hoc test. SS, sedentary + standard chow group; SD, sedentary + high-sugar diet group; TS, trained + standard chow group; TD, trained + high-sugar diet group.