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. 2016 Jun 29;116(3):1152–1160. doi: 10.1152/jn.00353.2016

Table 1.

Summary of SD parameters

Comparison Group % Latency, min # of Events Duration, min Delta [K+]o, mM
CS young 44 Mdn = 40.0 Mdn = 0.0 Mdn = 0.0 Mdn = 15.04
IQR = 8.89, 40.0 IQR = 0.0, 1.50 IQR = 0.0, 2.89 IQR = 11.39, 34.05
CS old 88 Mdn = 7.46 Mdn = 3.0 Mdn = 5.42 Mdn = 40.92
IQR = 2.57, 31.50 IQR = 1.25, 4.75* IQR = 3.19, 7.96* IQR = 12.71, 144.39
CS 67 Mdn = 13.98 Mdn = 1.0 Mdn = 1.65 Mdn = 29.28
IQR = 7.46, 40.0 IQR = 0.0, 4.0 IQR = 0.0, 11.22 IQR = 14.28, 46.45
w1118 100 Mdn = 3.23 Mdn = 6.50 Mdn = 16.66 Mdn = 37.86
IQR = 0.70, 10.84* IQR = 3.75, 9.0* IQR = 8.25, 27.52* IQR = 24.31, 65.41
forR 100 Mdn = 5.67 Mdn = 4.50 Mdn = 12.96 Mdn = 45.72
IQR = 2.67, 9.30 IQR = 3.0, 7.0 IQR = 7.22, 20.65 IQR = 28.23, 109.63
fors2 74 Mdn = 17.89 Mdn = 4.0 Mdn = 5.74 Mdn = 24.04
IQR = 7.46, 32.90* IQR = 1.0, 7.0 IQR = 1.06, 10.26* IQR = 18.63, 27.77*

Quantification of SD parameters for all flies tested. Three experimental comparisons were made: 1) young Canton S (CS; 4–5 days old) compared with old CS flies (35–40 days old); 2) CS flies compared with w1118 mutants; 3) forR (high PKG activity) compared with fors2 (low levels of PKG activity) flies. Percent (%), percent of preparations that exhibited SD in each group. Latency was measured from the time point of ouabain application to the inflection point of the first ouabain-induced event. Duration of SD activity was measured from the inflection point of the first SD event to the time of recovery following the last SD event. Delta [K+]o, overall change in [K+]o, calculated by measuring the [K+]o at the end of the 40-min treatment period and comparing it with initial levels before ouabain injections.

*

Significant differences between the corresponding flies within the comparison group. Details of the statistical tests performed and individual P values are reported in results.