Table 3: Investigation of Postural Tachycardia Syndrome According to the Heart Rhythm Society.
| Recommendation | CoR | LoE |
| A complete history and physical exam with orthostatic vital signs and 12-lead ECG should be performed in patients being investigated for POTS. | I | E |
| Complete blood count and thyroid function studies can be useful in selected patients being assessed for POTS. | IIa | E |
| A 24-hour Holter monitor might be considered in selected patients being assessed for POTS, although clinical efficiency is uncertain. | IIb | E |
| Detailed autonomic testing, transthoracic echocardiogram, tilt table testing, or exercise stress testing might be considered in selected patients being assessed for POTS. | IIb | E |
CoR = class of recommendation; LoE = level of evidence; POTS = postural orthostatic tachycardia syndrome.[1]