Table 2.
Individual neonatal morbidity outcomes in monochorionic and dichorionic twin pregnancies after 34 weeks’ gestation
| Gestational age | Assisted ventilation | Hypoxic ischaemic encephalopathy or neonatal seizures | Respiratory distress syndrome (RDS) | Septicaemia | NICU admission | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n/N | Risk* (95% CI) | n/N | Risk* (95% CI) | n/N | Risk* (95% CI) | n/N | Risk* (95% CI) | n/N | Risk* (95% CI) | |||||
| Monochorionic | ||||||||||||||
| No of studies | 7 | — | 7 | — | 10 | — | 11 | — | 9 | — | ||||
| 34+0-34+6 | 23/143 | 112.9 (49.2 to 238.3) | 0/101 | N/A | 38/178 | 176.7 (105.2 to 281.5) | 9/196 | 54.3 (23.9 to 118.8) | 61/157 | 501.6 (306.1 to 696.6) | ||||
| 35+0-35+6 | 17/206 | 61.3 (26.9 to 133.3) | 0/144 | N/A | 22/261 | 74.2 (43.6 to 123.7) | 7/283 | 24.4 (11.7 to 50.5) | 61/229 | 316.8 (173.2 to 506.6) | ||||
| 36+0-36+6 | 14/289 | 32.4 (13.7 to 74.3) | 1/238 | N/A | 13/365 | 29.1 (15.9 to 52.5) | 3/406 | 10.8 (4.6 to 24.9) | 44/319 | 176.1 (88.0 to 321.4) | ||||
| 37+0-37+6 | 7/308 | 16.9 (6.6 to 42.5) | 0/242 | N/A | 9/424 | 11.1 (5.3 to 22.8) | 3/452 | 4.7 (1.6 to 14.1) | 34/345 | 89.7 (41.3 to 183.9) | ||||
| 38+0-38+6 | 2/163 | 8.7 (3.0 to 25.0) | 0/137 | N/A | 0/225 | 4.2 (1.7 to 10.2) | 0/237 | 2.1 (0.5 to 8.5) | 5/168 | 43.4 (18.4 to 99.3) | ||||
| Dichorionic | ||||||||||||||
| No of studies | 9 | — | 2 | — | 13 | — | 11 | — | 11 | — | ||||
| 34+0-34+6 | 75/372 | 97.3 (36.4 to 235.4) | 1/190 | 3.6 (0.7 to 19.7) | 94/490 | 130.1 (77.8 to 209.6) | 11/465 | 9.5 (2.4 to 36.1) | 181/401 | 492.6 (317.4 to 669.6) | ||||
| 35+0-35+6 | 72/518 | 56.8 (20.9 to 145.6) | 1/304 | 2.8 (0.9 to 9.2) | 63/695 | 69.3 (40.9 to 114.9) | 6/659 | 6.4 (1.7 to 23.5) | 179/577 | 315.4 (182.3 to 487.8) | ||||
| 36+0-36+6 | 69/779 | 32.6 (11.8 to 86.9) | 1/530 | 2.2 (0.9 to 5.3) | 49/1013 | 35.7 (20.8 to 60.8) | 10/943 | 4.3 (1.2 to 15.7) | 152/853 | 179.5 (95.9 to 310.9) | ||||
| 37+0-37+6 | 41/1146 | 18.5 (6.5 to 51.0) | 1/820 | 1.7 (0.6 to 4.8) | 46/1563 | 18.1 (10.2 to 31.8) | 8/1447 | 2.9 (0.8 to 10.9) | 154/1296 | 94.1 (47.7 to 177.2) | ||||
| 38+0-38+6 | 21/834 | 10.4 (3.6 to 29.7) | 0/601 | 1.3 (0.3 to 5.9) | 17/1120 | 9.1 (4.9 to 16.7) | 7/1081 | 2.0 (0.5 to 7.8) | 77/932 | 47.0 (22.9 to 94.0) | ||||
| 39+0-39+6 | 2/103 | 5.8 (2.0 to 17.3) | 1/63 | 1.1 (0.1 to 8.2) | 1/258 | 4.5 (2.3 to 8.8) | 1/235 | 1.3 (0.3 to 5.8) | 5/134 | 22.9 (10.8 to 47.9) | ||||
NICU=neonatal intensive care unit; n=No of adverse outcomes; N=No of women delivered in that 1 week gestational time period.
*Risk/1000 deliveries.