Table 1. Characteristics of the Study Subjects.
| Matched cohort(N = 63,264) | Gout cohort(N = 63,264) | p-value | |
|---|---|---|---|
| Age (Mean ± SD) | 51.29 ± 16.25 | 51.29 ± 16.25 | 0.9890& |
| Age group | 0.9874$ | ||
| <20 | 1420 (2.24) | 1415 (2.24) | |
| 20–49 | 15106 (23.88) | 15094 (23.86) | |
| 50–64 | 26188 (41.39) | 26197 (41.41) | |
| 65–79 | 18891 (29.86) | 18935 (29.93) | |
| ≧80 | 1647 (2.60) | 1623 (2.57) | |
| Gender | 1.0000$ | ||
| Female | 16194 (25.60) | 16194 (25.60) | |
| Male | 47070 (74.40) | 47070 (74.40) | |
| Comorbidities | |||
| DM | 4867 (7.69) | 8933 (14.12) | <0.0001$ |
| CKD | 446 (0.70) | 1087 (1.72) | <0.0001$ |
| HTN | 11153 (17.63) | 23412 (37.01) | <0.0001$ |
| Hyperlipidemia | 4719 (7.46) | 17119 (27.06) | <0.0001$ |
| COPD | 1583 (2.50) | 2199 (3.48) | <0.0001$ |
| CAD | 4779 (7.55) | 8868 (14.02) | <0.0001$ |
| History of cardiac or pulmonary surgery | 28 (0.04) | 48 (0.08) | 0.0217$ |
| Alcoholic intoxication | 91 (0.14) | 242 (0.38) | <0.0001$ |
| Sleep apnea | 82 (0.13) | 150 (0.24) | <0.0001$ |
| CHF | 1365 (2.16) | 2783 (4.40) | <0.0001$ |
| Rheumatoid arthritis | 253 (0.4) | 856 (1.35) | <0.0001$ |
| SLE | 51 (0.08) | 84 (0.13) | 0.0045$ |
| Scleroderma | 6 (0.01) | 12 (0.02) | 0.1573$ |
| Sjögren’s syndrome | 135 (0.21) | 161 (0.25) | 0.1303$ |
| Atrial fibrillation | 1924 (3.04) | 2917 (4.61) | <0.0001$ |
The statistical analyses were performed by t-test or Chi-square test. Symbols (&, $) indicate significance (at p < 0.05 level). &: T-test; $: Chi-squared test; DM: diabetes mellitus; CKD: chronic kidney disease; HTN: hypertension; CHF: congestive heart failure; COPD: chronic obstructive pulmonary disease; CAD: coronary artery disease; SLE: systemic lupus erythematosus.