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. 2016 Sep 7;6:32220. doi: 10.1038/srep32220

Table 3. Prediction of occurrence of atrial fibrillation stratified by gender and age.

  Male Female <65 > = 65
  cHRs (95% C.I.) p-value aHRs (95% C.I.) p-value cHRs (95% C.I.) p-value aHRs (95% C.I.) p-value
Gout vs. matched 1.41 (1.29–1.55) <0.0001 1.29 (1.12–1.48) 0.0005 1.62 (1.42–1.84) <0.0001 1.25 (1.14–1.38) <0.0001
 Age 1.33 (1.06–1.65) 0.0121 1.08 (0.79–1.48) 0.6185 1.36 (1.00–1.84) 0.0477 1.17 (0.93–1.47) 0.1776
Comorbidities
 DM 0.98 (0.81–1.19) 0.8333 1.47 (1.16–1.85) 0.0013 1.37 (1.04–1.80) 0.0233 1.05 (0.88–1.25) 0.6184
 CKD 1.77 (1.08–2.91) 0.0239 0.97 (0.53–1.78) 0.9271 3.01 (1.12–8.10) 0.0291 1.27 (0.82–1.95) 0.2849
 HTN 1.21 (1.05–1.40) 0.0101 1.31 (1.06–1.62) 0.0114 1.35 (1.10–1.67) 0.0049 1.15 (0.99–1.33) 0.0659
 COPD 1.01 (0.79–1.29) 0.9496 0.87 (0.56–1.35) 0.5330 1.08 (0.60–1.97) 0.794 0.98 (0.78–1.23) 0.8423
 CAD 1.57 (1.32–1.87) <0.0001 1.43 (1.13–1.79) 0.0026 1.59 (1.20–2.12) 0.0014 1.50 (1.28–1.77) <0.0001
 HCPS* 1.99 (0.37–10.69) 0.4203     2.13 (0.41–11.06) 0.3673
 AI^ 1.76 (0.50–6.19) 0.3823   0.90 (0.19–4.38) 0.8997 4.17 (0.44–39.45) 0.2132
 Sleep apnea 1.45 (0.37–5.66) 0.5964   1.00 (0.14–7.46) 0.9986 1.23 (0.20–7.48) 0.8211
 CHF 3.40 (2.48–4.68) <0.0001 2.21 (1.58–3.10) <0.0001 9.90 (4.13–23.75) <0.0001 2.37 (1.85–3.02) <0.0001
 RA 0.84 (0.41–1.74) 0.6408 1.16 (0.57–2.36) 0.6745 1.39 (0.60–3.23) 0.4378 0.88 (0.46–1.68) 0.7016
 SLE 0.73 (0.10–5.27) 0.7534   2.20 (0.19–25.66) 0.5299 1.60 (0.13–20.22) 0.7146
 Scleroderma   0.46 (0.02–10.61) 0.6272    
 SS& 1.00 (0.30–3.29) 0.9995 1.36 (0.36–5.18) 0.6485 0.42 (0.10–1.85) 0.2522 1.64 (0.59–4.54) 0.3394

The statistical analysis was performed with the Cox proportional hazards regression model to indicate significance (at p < 0.05 level).

aHRs: adjusted hazard ratios; cHRs: crude hazard ratios; CI: confidence interval; AI^: alcoholic intoxication; HCPS*: history of cardiac or pulmonary surgery; SS&: Sjögren’s syndrome; other abbreviations are as described in Table 1.