Table 3. Prediction of occurrence of atrial fibrillation stratified by gender and age.
Male | Female | <65 | > = 65 | |||||
---|---|---|---|---|---|---|---|---|
cHRs (95% C.I.) | p-value | aHRs (95% C.I.) | p-value | cHRs (95% C.I.) | p-value | aHRs (95% C.I.) | p-value | |
Gout vs. matched | 1.41 (1.29–1.55) | <0.0001 | 1.29 (1.12–1.48) | 0.0005 | 1.62 (1.42–1.84) | <0.0001 | 1.25 (1.14–1.38) | <0.0001 |
Age | 1.33 (1.06–1.65) | 0.0121 | 1.08 (0.79–1.48) | 0.6185 | 1.36 (1.00–1.84) | 0.0477 | 1.17 (0.93–1.47) | 0.1776 |
Comorbidities | ||||||||
DM | 0.98 (0.81–1.19) | 0.8333 | 1.47 (1.16–1.85) | 0.0013 | 1.37 (1.04–1.80) | 0.0233 | 1.05 (0.88–1.25) | 0.6184 |
CKD | 1.77 (1.08–2.91) | 0.0239 | 0.97 (0.53–1.78) | 0.9271 | 3.01 (1.12–8.10) | 0.0291 | 1.27 (0.82–1.95) | 0.2849 |
HTN | 1.21 (1.05–1.40) | 0.0101 | 1.31 (1.06–1.62) | 0.0114 | 1.35 (1.10–1.67) | 0.0049 | 1.15 (0.99–1.33) | 0.0659 |
COPD | 1.01 (0.79–1.29) | 0.9496 | 0.87 (0.56–1.35) | 0.5330 | 1.08 (0.60–1.97) | 0.794 | 0.98 (0.78–1.23) | 0.8423 |
CAD | 1.57 (1.32–1.87) | <0.0001 | 1.43 (1.13–1.79) | 0.0026 | 1.59 (1.20–2.12) | 0.0014 | 1.50 (1.28–1.77) | <0.0001 |
HCPS* | 1.99 (0.37–10.69) | 0.4203 | — | — | 2.13 (0.41–11.06) | 0.3673 | ||
AI^ | 1.76 (0.50–6.19) | 0.3823 | — | 0.90 (0.19–4.38) | 0.8997 | 4.17 (0.44–39.45) | 0.2132 | |
Sleep apnea | 1.45 (0.37–5.66) | 0.5964 | — | 1.00 (0.14–7.46) | 0.9986 | 1.23 (0.20–7.48) | 0.8211 | |
CHF | 3.40 (2.48–4.68) | <0.0001 | 2.21 (1.58–3.10) | <0.0001 | 9.90 (4.13–23.75) | <0.0001 | 2.37 (1.85–3.02) | <0.0001 |
RA | 0.84 (0.41–1.74) | 0.6408 | 1.16 (0.57–2.36) | 0.6745 | 1.39 (0.60–3.23) | 0.4378 | 0.88 (0.46–1.68) | 0.7016 |
SLE | 0.73 (0.10–5.27) | 0.7534 | — | 2.20 (0.19–25.66) | 0.5299 | 1.60 (0.13–20.22) | 0.7146 | |
Scleroderma | — | — | — | 0.46 (0.02–10.61) | 0.6272 | |||
SS& | 1.00 (0.30–3.29) | 0.9995 | 1.36 (0.36–5.18) | 0.6485 | 0.42 (0.10–1.85) | 0.2522 | 1.64 (0.59–4.54) | 0.3394 |
The statistical analysis was performed with the Cox proportional hazards regression model to indicate significance (at p < 0.05 level).
aHRs: adjusted hazard ratios; cHRs: crude hazard ratios; CI: confidence interval; AI^: alcoholic intoxication; HCPS*: history of cardiac or pulmonary surgery; SS&: Sjögren’s syndrome; other abbreviations are as described in Table 1.