TABLE 1 .
List of regulated noncoding RNAs identified in this study
Start (bp)a,b | Stop (bp)a,b | Strand | Description | TF regulator(s) | Fold changec |
---|---|---|---|---|---|
34013* | 33811* | − | Antisense to STM14_5565 | HilC | 2.28d |
74905 | 74971 | + | DapZ | RtsA | 2.66 |
868925 | 868081 | − | Antisense to slrP | RtsA | 1.25 |
1343788 | 1343659 | − | STnc520 | SprB | 4.08 |
1418433 | 1418523 | + | Overlapping STM14_1613/STM14_1614 | HilC | 1.18 |
1603873 | 1604092 | + | MgrR | HilD | 2.12 |
1603938 | 1603781 | − | Overlapping STM14_1833 | HilD, RtsA | 3.73, 2.05e |
3039507 | 3039347 | − | Antisense to hilA 5′ UTR | HilD | 4.23 |
3065151 | 3066061 | + | InvR | HilD, HilC | 1.07, 3.99e |
3483808 | 3483985 | + | Within dacB | RtsA | 2.54 |
The numbers represent predicted start/stop genome coordinates for a given noncoding RNA (ncRNA). Numbers marked with an asterisk indicate RNAs encoded on the virulence plasmid.
In some cases, multiple, overlapping fragments of an ncRNA were identified, or overlapping ncRNAs were identified for multiple TFs. These instances were merged into a single unit.
Data represent fold change (log2) in RNA level for cells showing overexpression of the corresponding TF versus cells in which the TF-encoding gene was deleted.
Data represent averages of fold change values for three overlapping transfrags.
The two values correspond to the 2 TFs, in the order listed in the previous column.