Table 1.
Characteristics and relative risks of severe sepsis among pregnant and recently pregnant women
| Total | Critical care admissions | All maternities | Relative risk (95% CI) |
|---|---|---|---|
| 646 (100.0) | 2 186 818 | ||
| Recently pregnant | 413 (63.9) | ||
| Maternal age, years (mean; SD) | 28.3 (6.9) | 29.0 (–) | |
| <20 | 80 (12.4) | 129 167 (5.9) | 2.5 (1.9 to 3.3) |
| 20–24 | 133 (20.6) | 419 944 (19.2) | 1.3 (1.0 to 1.6) |
| 25–29 | 148 (23.0) | 602 716 (27.6) | 1 |
| 30–34 | 153 (23.7) | 600 694 (27.5) | 1.0 (0.8 to 1.3) |
| 35–39 | 95 (14.7) | 352 364 (16.1) | 1.1 (0.9 to 1.4) |
| ≥40 | 36 (5.6) | 81 933 (3.7) | 1.8 (1.2 to 2.6) |
| Non-white ethnicity | 154 (23.8) | 609 250 (27.9) | 0.9 (0.8 to 1.0) |
| Index of multiple deprivation (quintiles)* | |||
| 1 (least deprived) | 63 (10.1) | 589 784 (27.6) | 1 |
| 2 | 75 (12.0) | 475 573 (22.2) | 1.5 (1.1 to 2.1) |
| 3 | 109 (17.5) | 395 137 (18.5) | 2.6 (1.9 to 3.5) |
| 4 | 148 (23.8) | 346 002 (16.2) | 4.0 (3.0 to 5.4) |
| 5 (most deprived) | 228 (36.6) | 330 916 (15.5) | 6.5 (4.9 to 8.5) |
| BMI, kg/m2 (median; IQR)* (N=312) | 26 (22–30) | ||
| History of immunosuppression | 15 (2.3) | ||
| Weeks gestation | |||
| Antenatal (median; IQR) | 26 (20–31) | ||
| Postnatal (median; IQR) | 38 (31–41) | ||
| Recently pregnant women only | |||
| Parity* | |||
| 0 | 193 (48.4) | ||
| 1 | 96 (24.1) | ||
| ≥2 | 110 (27.6) | ||
| Assisted conception* | 24 (8.1) | ||
| Mode of delivery† | |||
| Spontaneous vaginal | 98 (25.9) | 1 334 242 (61.0) | 1 |
| Assisted vaginal | 28 (7.4) | 273 340 (12.5) | 1.4 (0.9 to 2.1) |
| Caesarean section | 242 (64.0) | 535 999 (24.5) | 6.2 (4.9 to 7.8) |
| Unknown | 10 (2.7) | ||
| All multiple births (live births and stillbirths) | 28 (7.6) | 34 663 (1.6) | 4.4 (3.1 to 6.3) |
| Pregnancy outcomes | |||
| Live births | 321 (77.7) | ||
| Stillbirths | 47 (11.4) | 11 697 (0.5%) | 21.3 (16.3 to 27.9) |
| 1st/2nd trimester loss | 25 (6.1) | ||
| Ectopic pregnancy | 10 (2.4) | ||
| Other‡ | 2 (0.5) | ||
| Unknown | 10 (2.4) | ||
| Hysterectomy* | 20 (5.4) | ||
| Days since delivery (median; IQR) | 3 (0–8) | ||
Bold typeface indicates statistically significant results. Figures are N (%) unless otherwise stated.
1=Reference Group.
*Of those reported.
†National rates are total deliveries.
‡Two women each had one live birth and one stillbirth from the most recent pregnancy.
BMI, body mass index.