Table 2. Characteristics of the association studies between 4 SNPs of FKBP5 included for meta-analysis and MDD.

SNP (Major/minor allele)	Position	Author, year	Ethinicity	aN cases/N controls	Minor allele frequency		P-value	OR (95% CI)
					Cases	Controls
rs1360780 (C/T)	Chr6: 35639794	Szczepankiewicz, 2014	Poland	218/762	0.280	0.257	0.372	1.121 (0.872–1.442)
		Minelli, 2013	Italy	657/462	0.312	0.332	0.313	0.912 (0.761–1.091)
		Zobel, 2010	Germany	268/284	0.281	0.339	0.036	0.762 (0.590–0.984)
		Lavebratt, 2010	Sweden	431/2204	0.268	0.265	0.844	1.107 (0.862–1.199)
		Lekman, 2008	USA	1520/769	0.346	0.304	0.005	1.210 (1.060–1.380)
		Papiol, 2007	Spain	157/91	0.334	0.297	0.386	1.191 (0.802–1.768)
		Psychiatric GWAS Consortium, 2013	bEuropean	9240/9519	*See below	*See below	0.039	1.049 (1.002–1.098)
rs755658 (C/T)	Chr6: 35581893	Szczepankiewicz, 2014	Poland	211/520	0.104	0.090	0.411	1.171 (0.803–1.708)
		Zobel, 2010	Germany	268/284	0.094	0.122	0.126	0.744 (0.506–1.093)
		Psychiatric GWAS Consortium, 2013	European	9240/9519	*See below	*See below	0.067	1.068 (0.995–1.146)
rs4713916 (G/A)	Chr6: 35702206	Szczepankiewicz, 2014	Poland	222/521	0.284	0.258	0.306	1.139 (0.888–1.460)
		Zobel, 2010	Germany	268/284	0.273	0.341	0.014	0.722 (0.558–0.934)
		Lekman, 2008	USA	1523/739	0.275	0.261	0.322	1.074 (0.933–1.236)
rs3800373 (A/C)	Chr6: 35574699	Szczepankiewicz, 2014	Poland	220/516	0.255	0.244	0.673	1.057 (0.817–1.367)
		Zobel, 2010	Germany	268/284	0.255	0.322	0.014	0.722 (0.556–0.939)
		Lekman, 2008	USA	1496/691	0.328	0.298	0.052	1.147 (0.999–1.317)
		Psychiatric GWAS Consortium, 2013	European	9240/9519	*See below	*See below	0.011	1.062 (1.014–1.113)

^aThe N represents the number of individuals having genotyping data.

^bsamples from 9 distinct populations of European ancestry.

^*Only the MAF of the overall samples available (rs1360780: 0.308; rs755668: 0.067; rs3800373: 0.291).