Table 2. Interpretation of CBDDIN colors allocated by the modularity clustering algorithm.
| Modularity class (color) | Code | Modularity class interpretation | No. of drugs | Consistency [%] |
|---|---|---|---|---|
| Dark blue | DB | Central and peripheral nervous system acting drugs | 232 | 96 |
| Velvet maroon | VM | Substrates, inhibitors and inducers of specific CYP enzymes | 210 | 91 |
| Green | G | Drugs that interfere in different phases of hemostasis, anticonvulsant and epileptogenic drugs | 191 | 85 |
| Magenta | M | Drugs acting on sympathetic nervous system | 166 | 93 |
| Light blue | LB | Drugs targeting cancer, auto-immune disorders (i.e. rheumatoid arthritis), and musculoskeletal system | 156 | 88 |
| Golden brown | GB | Drugs interfering with platelet activity and plasma potassium levels | 155 | 92 |
| Purple | P | Bi-and trivalent cations, chelating agents | 31 | 100 |
The tags are allocated to modularity classes according to pharmacological properties (column Modularity class interpretation). The number of drugs pertaining to each modularity class, along with the percentage of drugs that abide by the color interpretation, are also provided (columns No. of drugs and Consistency [%], respectively).