Table 4.
Adverse events related to the study drug reported within 2, 3, and 4 yr of the patient's first dose
| Patients reporting drug-related AEs, n (%) |
|||
|---|---|---|---|
| Within 2 yr of first dosea | Within 3 yr of first doseb | Within 4 yr of first dosec | |
| Any drug-related AEd | 120 (86) | 121 (86) | 121 (86) |
| Fatigue | 80 (57) | 82 (59) | 82 (59) |
| Nausea | 45 (32) | 46 (33) | 46 (33) |
| Anorexia | 21 (15) | 21 (15) | 21 (15) |
| Dysgeusia | 19 (14) | 19 (14) | 19 (14) |
| Hot flush | 19 (14) | 20 (14) | 20 (14) |
| Dizziness | 18 (13) | 19 (14) | 19 (14) |
| Diarrhea | 12 (8.6) | 13 (9.3) | 15 (11) |
AE = adverse event.
a
24 patients remaining in the study.
b
15 patients remaining in the study.
c
12 patients remaining in the study.
d
Events listed are those reported by ≥10% of patients for at least one time point.