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. 2016 Sep 6;16:74. doi: 10.1186/s12871-016-0235-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a-b Paw withdrawal mechanical threshold (a) and paw withdrawal thermal latency (b) were evaluated at 24 h before incision and 2, 6, 24, 48 and 72 h after remifentanil infusion. Groups allocation: R: Group remifentanil; RI: Group remifentanil + surgical incision; C: Group Control; I: Group surgical incision. Data are expressed as means ± SD. * P < 0.001 compared with Group C, # P < 0.001 compared with Group RI, + P < 0.05 compared with Group R