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. 2015 Oct 5;149(1):111–120. doi: 10.1093/toxsci/kfv213

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Published by Oxford University Press on behalf of the Society of Toxicology 2015. This work is written by US Government employees and is in the public domain in the US.

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FIG. 3. — CDDO-EA reduces CCl₄-induced fibrosis without altering CYP2E1 levels compared with CCl₄ treatment. A, mRNA and protein expression expression of CYP2E1 was assessed at 30 weeks post CCl₄ treatment versus CCl₄ + CDDO-EA. Histogram depicts relative density units of protein expression. B, Acute effect of CCl₄ was assessed with measurement of ALT, mRNA and protein expression expression of CYP2E1. Protein expression was assessed via Western blot analysis. Data are presented as mean ± SE (n = 10 per group). Each experiment was performed in duplicate. *P < .05, **P < .01, ***P < .001.