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Adverse Reactions Reported in ≥5% of Patients Receiving Sacubitril plus Valsartan versus Enalapril in the PARADIGM-HF Study
| Adverse event | Sacubitril plus valsartan, % (N = 4203) | Enalapril, % (N = 4229) |
|---|---|---|
| Hypotension | 18 | 12 |
| Hyperkalemia | 12 | 14 |
| Cough | 9 | 13 |
| Dizziness | 6 | 5 |
| Renal failure or acute renal failure | 5 | 5 |
Source: Entresto (sacubitril and valsartan) tablets prescribing information; July 2015.
