Table 5.
Associations Between Maternal Gestational Levels of Creatinine-Basis Mean Dialkylphosphate Metabolite Urinary Concentrations and Wechsler Preschool and Primary Scale of Intelligence, Third Edition, Among Children Enrolled at Age 5 Years in a Cincinnati-Based Pregnancy Cohort (The HOME Study) Between 2003 and 2006
Organophosphate | Wechsler Preschool and Primary Scale of Intelligence, Third Edition |
|
---|---|---|
Estimate (Standard Error) | P Value | |
Full-Scale IQ | ||
Total DAPa | 0.004 (0.002) | 0.111 |
Total DAPb | 0.001 (0.002) | 0.494 |
Total DMa | 0.004 (0.003) | 0.124 |
Total DMb | 0.002 (0.002) | 0.441 |
Total DEa | 0.031 (0.029) | 0.289 |
Performance IQ | ||
Total DAPa | 0.003 (0.003) | 0.277 |
Total DMa | 0.003 (0.003) | 0.265 |
Total DEa | −0.001 (0.030) | 0.979 |
Verbal IQ | ||
Total DAPa | 0.005 (0.002) | 0.034 |
Total DAPc | 0.003 (0.002) | 0.179 |
Total DMa | 0.005 (0.002) | 0.043 |
Total DMc | 0.003 (0.002) | 0.144 |
Total DEa | 0.048 (0.029) | 0.099 |
Total DEc | −0.027 (0.024) | 0.259 |
Abbreviations: DAP, dialkylphosphate; DE, diethylphosphate; DM, dimethylphosphate; HOME Study, Health Outcomes and Measures of the Environment Study; IQ, intelligence quotient.
a Unadjusted model.
b Adjusted for household income, maternal race, child's sex, maternal intelligence quotient; and maternal education.
c Adjusted for household income, maternal race, child sex, maternal intelligence quotient; Home inventory score, maternal age at birth, alcohol consumption during pregnancy, and parity.