Table 3.

Comb-p differentially methylated region analysis.

Region	CpG sites in region	p value	Adjusted p value
CD-associated DMRs
Chr1: 2230601–2230924	4	7.66e–12	2.09e–06
Chr14: 24540174–24540453	4	3.44e–09	0.001087
Chr11: 65546988–65547173	4	1.02e–08	0.004868
Chr2: 128458240–128458402	5	5.18e–25	2.82e–19
Chr6: 6588693–6589076	5	1.11e–16	2.56e–11
Chr22: 45608345–45608714	10	3.60e–15	8.50e–10
Chr6: 30297174–30297628	11	1.88e–18	3.65e–13
UC-associated DMRs
Chr2: 128458240–128458402	5	9.30e–13	5.07e–07
Chr6: 30297257–30297628	10	2.61e–11	6.21e–06

CD, Crohn’s disease; UC, ulcerative colitis.

p value, slk-corrected p value; Adjusted p value, one-step Šidák multiple-testing correction.

Differentially methylated regions associated with IBD are highlighted in bold.