Table 3.
Association of Baseline CPC Types With 3-month Assessments of Physical Function
| CD34+ | CD133+ | CD34+CD133+ | ALDHbr | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted* | Unadjusted | Adjusted* | Unadjusted | Adjusted* | Unadjusted | Adjusted* | |||||||||
| Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | |
| Usual gait speed (m/s) | 0.073 (0.023) | .002 | 0.065 (0.022) | .003 | 0.068 (0.025) | .006 | 0.071 (0.022) | .002 | 0.088 (0.024) | .0003 | 0.084 (0.022) | .0003 | 0.064 (0.023) | .007 | 0.060 (0.022) | .008 |
| Rapid gait speed (m/s) | 0.101 (0.036) | .006 | 0.086 (0.034) | .014 | 0.086 (0.038) | .027 | 0.089 (0.036) | .015 | 0.102 (0.038) | .009 | 0.089 (0.036) | .016 | 0.106 (0.036) | .004 | 0.080 (0.035) | .012 |
| 6-min walk distance (ft) | 74.4 (33.1) | .027 | 59.6 (28.0) | .036 | 52.2 (35.2) | .14 | 56.8 (29.4) | .056 | 70.6 (34.6) | .044 | 59.8 (29.5) | .045 | 68.8 (33.0) | .039 | 55.4 (28.9) | .058 |
| SF-36 physical function score | 3.02 (2.05) | .144 | 1.57 (1.92) | .42 | 3.01 (2.16) | .17 | 2.73 (1.99) | .17 | 2.81 (2.16) | .19 | 1.77 (2.04) | .39 | 2.39 (2.08) | .25 | 0.77 (1.99) | .70 |
| Time for five chair stands (s) | −0.56 (0.32) | .086 | −0.37 (0.32) | .25 | −0.40 (0.34) | .24 | −0.36 (0.34) | .28 | −0.47 (0.34) | .17 | −0.31 (0.34) | .37 | −0.67 (0.33) | .041 | −0.49 (0.33) | .14 |
Notes: CPC = circulating progenitor cell; Est = parameter estimate; SE = standard error of parameter estimate.
*Adjusted for age, arm, body mass index, comorbid conditions, and IL-6 level.