Table 4.
Association of Baseline CPC Types With 12-Month Assessments of Physical Function
| CD34+ | CD133+ | CD34+CD133+ | ALDHbr | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted* | Unadjusted | Adjusted* | Unadjusted | Adjusted* | Unadjusted | Adjusted* | |||||||||
| Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | Est (SE) | p Value | |
| Usual gait speed (m/s) | 0.057 (0.026) | .032 | 0.041 (0.024) | .087 | 0.057 (0.027) | .035 | 0.052 (0.024) | .033 | 0.067 (0.028) | .018 | 0.055 (0.025) | .031 | 0.028 (0.027) | .30 | 0.028 (0.025) | .26 |
| Rapid gait speed (m/s) | 0.141 (0.042) | .001 | 0.126 (0.042) | .003 | 0.109 (0.044) | .016 | 0.111 (0.043) | .011 | 0.147 (0.046) | .002 | 0.137 (0.044) | .003 | 0.106 (0.044) | .018 | 0.109 (0.043) | .013 |
| 6-min walk distance (ft) | 100.3 (38.8) | .023 | 70.1 (31.2) | .028 | 106.6 (40.4) | .019 | 89.1 (30.6) | .005 | 86.0 (41.6) | .069 | 77.8 (33.4) | .023 | 61.6 (38.2) | .15 | 47.8 (31.6) | .14 |
| SF-36 physical function score | 4.56 (2.31) | .051 | 3.28 (2.20) | .14 | 3.43 (2.42) | .916 | 3.54 (2.22) | .12 | 2.33 (2.50) | .35 | 2.04 (2.37) | .39 | 3.26 (2.30) | .16 | 1.30 (2.27) | .57 |
| Time for five chair stands (s) | −0.71 (0.35) | .047 | −0.53 (0.35) | .136 | −0.76 (0.36) | .036 | −0.67 (0.35) | .057 | −0.68 (0.37) | .07 | −0.56 (0.37) | .14 | −0.56 (0.35) | .11 | −0.36 (0.36) | .32 |
Notes: CPC = circulating progenitor cell; Est = parameter estimate; SE = standard error of parameter estimate.
*Adjusted for age, arm, body mass index, comorbid conditions, and IL-6 level.